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Topics and Techniques in International Population Health: Sociogenomic Research

Course Date: June 10

Days: F (11:00 AM-2:00 PM)

International and comparative population research is a key cornerstone of population science and demography. International and comparative research is essential: 1. to learn the variations in population dynamics across different populations; 2. to predict the future of global population trends; and 3. to test hypotheses across widely varying context and determine the limits on forces producing population change. This five-day workshop on international and comparative population research begins with a review of the field and deep-dive into data creation for this science. Although students are encouraged to attend all 5 days of the workshop, students may attend any combination of the 5 days to meet their training needs. Each day of the workshop is structured as an independent, ½-day, short course. Chitwan Valley Family Study (CVFS) will be used as a featured example and compared to other international population studies as appropriate for the topics. The workshop will meet daily June 6 – June 10 from 11:00 a.m. – 2:00 p.m, Eastern Standard Time. Support for this workshop is provided by NICHD (R25 HD101358).

This is the fifth day of a 5-day workshop on international research using the Chitwan Valley Family Study (CVFS) as a featured case study, but will draw on several data resources. This short course briefly introduces students to the major issues surrounding using genomic data to study health and behavior in lower- and middle-income countries (LMICs). The first major topic includes introductions into common methods of DNA sample collection strategies, including the costs and benefits of each, and common pitfalls in the collection and assaying of DNA. Discussions of major ethical and conceptual issues to consider in designing a genomic study will be covered. Following this is a discussion of common analytic strategies used in health and sociogenomic research, including, genome wide association studies, polygenic scores, family models, and gene-environment interactions. The course concludes with potential week-long, semester, and year-long courses to follow-up in more detail. This course is both a guide to next steps for genomic work in international settings and also to the genomic data of CVFS. For more information on the Chitwan Valley Family Study (CVFS), visit: https://cvfs.isr.umich.edu/. Support for this workshop is provided by NICHD (R25 HD101358).

For funding information please visit,  https://cvfs.isr.umich.edu/news/

Instructor: Colter Mitchell